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1

Mitochondria in cancer cells: what is so special about them?

Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Trends in Cell Biology

Year:

2008

Language:

english

File:

PDF, 495 KB

english, 2008

2

Mitochondrial Oxidative Stress: Implications for Cell Death

Orrenius, Sten, Gogvadze, Vladimir, Zhivotovsky, Boris

Journal:

Annual Review of Pharmacology

Year:

2007

Language:

english

File:

PDF, 461 KB

english, 2007

3

Mitochondria, oxidative stress and cell death

Martin Ott, Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Year:

2007

Language:

english

File:

PDF, 325 KB

english, 2007

4

Release of mitochondrial DNA fragments from brain mitochondria of irradiated mice

Maxim Patrushev, Vitaliy Kasymov, Valeria Patrusheva, Tatiana Ushakova, Vladimir Gogvadze, Azhub I. Gaziev

Journal:

Year:

2006

Language:

english

File:

PDF, 112 KB

english, 2006

5

The role of Fe2+-induced lipid peroxidation in the initiation of the mitochondrial permeability transition

Vladimir Gogvadze, Patrick B Walter, Bruce N Ames

Journal:

Archives of Biochemistry and Biophysics

Year:

2003

Language:

english

File:

PDF, 133 KB

english, 2003

6

Contrasting effects of α-tocopheryl succinate on cisplatin- and etoposide-induced apoptosis

Kruspig, Björn, Zhivotovsky, Boris, Gogvadze, Vladimir

Journal:

Year:

2013

Language:

english

File:

PDF, 505 KB

english, 2013

7

Calcium and mitochondria in the regulation of cell death

Orrenius, Sten, Gogvadze, Vladimir, Zhivotovsky, Boris

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 764 KB

english, 2015

8

Targeting Mitochondria in Fighting Cancer

Gogvadze, Vladimir

Journal:

Current Pharmaceutical Design

Year:

2011

Language:

english

File:

PDF, 392 KB

english, 2011

9

2-Deoxyglucose has distinct and cell line-specific effects on the survival of different cancer cells upon antitumor drug treatment

Maximchik, Polina, Abdrakhmanov, Alibek, Inozemtseva, Evgeniya, Tyurin-Kuzmin, Pyotr A., Zhivotovsky, Boris, Gogvadze, Vladimir

Journal:

Year:

2018

Language:

english

File:

PDF, 1.67 MB

english, 2018

10

Involvement of Ca2+ and ROS in α-tocopheryl succinate-induced mitochondrial permeabilization

Vladimir Gogvadze, Erik Norberg, Sten Orrenius, Boris Zhivotovsky

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 770 KB

english, 2010

11

A folding variant of human α-lactalbumin induces mitochondrial permeability transition in isolated mitochondria

Camilla Köhler, Vladimir Gogvadze, Anders Håkansson, Catharina Svanborg, Sten Orrenius, Boris Zhivotovsky

Journal:

Year:

2001

Language:

english

File:

PDF, 476 KB

english, 2001

12

Resveratrol induces SIRT1- and energy–stress-independent inhibition of tumor cell regrowth after low-dose platinum treatment

My Björklund, Jeanette Roos, Vladimir Gogvadze, Maria Shoshan

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 725 KB

english, 2011

13

Mitochondria as targets for chemotherapy

Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Year:

2009

Language:

english

File:

PDF, 420 KB

english, 2009

14

Alteration of mitochondrial function and cell sensitization to death

Vladimir Gogvadze, Boris Zhivotovsky

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2007

Language:

english

File:

PDF, 241 KB

english, 2007

15

Hippocampal Neurons Exposed to the Environmental Contaminants Methylmercury and Polychlorinated Biphenyls Undergo Cell Death via Parallel Activation of Calpains and Lysosomal Proteases

Roshan Tofighi, Carolina Johansson, Matteo Goldoni, Wan Norhamidah Wan Ibrahim, Vladimir Gogvadze, Antonio Mutti, Sandra Ceccatelli

Journal:

Neurotoxicity Research

Year:

2011

Language:

english

File:

PDF, 624 KB

english, 2011

16

Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF

Maryam Nikpour, Andrea Pellagatti, Anquan Liu, Mohsen Karimi, Luca Malcovati, Vladimir Gogvadze, Ann-Mari Forsblom, James S. Wainscoat, Mario Cazzola, Boris Zhivotovsky, Alf Grandien, Jacqueline Boult

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 598 KB

english, 2010

17

Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity

Robertson, John D, Gogvadze, Vladimir, Kropotov, Andrey, Vakifahmetoglu, Helin, Zhivotovsky, Boris, Orrenius, Sten

Journal:

Year:

2004

Language:

english

File:

PDF, 204 KB

english, 2004

18

Targeting mitochondria byα-tocopheryl succinate kills neuroblastoma cells irrespective ofMycNoncogene expression

Kruspig, Björn, Nilchian, Azadeh, Bejarano, Ignacio, Orrenius, Sten, Zhivotovsky, Boris, Gogvadze, Vladimir

Journal:

Cellular and Molecular Life Sciences

Year:

2012

Language:

english

File:

PDF, 542 KB

english, 2012

19

The effect of dietary supplements on gene expression in mice tissues

Tatyana Ushakova, Hovsep Melkonyan, Larisa Nikonova, Nicolai Mudrik, Vladimir Gogvadze, Alexandra Zhukova, Azhub I. Gaziev, Robert Bradbury

Journal:

Free Radical Biology and Medicine

Year:

1996

Language:

english

File:

PDF, 572 KB

english, 1996

20

Mitochondrial regulation of apoptotic cell death

Vladimir Gogvadze, Sten Orrenius

Journal:

Chemico-Biological Interactions

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

21

Hypomethylation and apoptosis in 5-azacytidine–treated myeloid cells

Rasheed Khan, Jan Schmidt-Mende, Mohsen Karimi, Vladimir Gogvadze, Moustapha Hassan, Tomas J. Ekström, Boris Zhivotovsky, Eva Hellström-Lindberg

Journal:

Experimental Hematology

Year:

2008

Language:

english

File:

PDF, 882 KB

english, 2008

22

Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processing

Erik Norberg, Vladimir Gogvadze, Helin Vakifahmetoglu, Sten Orrenius, Boris Zhivotovsky

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 792 KB

english, 2010

23

Multiple roles of microsomal glutathione transferase 1 in cellular protection: A mechanistic study

Katarina Johansson, Julia Järvliden, Vladimir Gogvadze, Ralf Morgenstern

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 898 KB

english, 2010

24

Mitochondria as targets for cancer chemotherapy

Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Seminars in Cancer Biology

Year:

2009

Language:

english

File:

PDF, 377 KB

english, 2009

25

Arsenic stimulates release of cytochrome c from isolated mitochondria via induction of mitochondrial permeability transition

Juanita Bustamante, Leta Nutt, Sten Orrenius, Vladimir Gogvadze

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 278 KB

english, 2005

26

Control of the pyridine nucleotide-linked Ca2+ release from mitochondria by respiratory substrates

Vladimir Gogvadze, Matthias Schweizer, Christoph Richter

Journal:

Year:

1996

Language:

english

File:

PDF, 583 KB

english, 1996

27

Modification of gene expression by dietary antioxidants in radiation-induced apoptosis of mice splenocytes

Tatyana Ushakova, Hovsep Melkonyan, Larisa Nikonova, Vladimir Afanasyev, Azhub I Gaziev, Nikolai Mudrik, Robert Bradbury, Vladimir Gogvadze

Journal:

Free Radical Biology and Medicine

Year:

1999

Language:

english

File:

PDF, 119 KB

english, 1999

28

Fe2+ Induces a Transient Ca2+ Release from Rat Liver Mitochondria

Vladimir Gogvadze, Patrick B. Walter, Bruce N. Ames

Journal:

Archives of Biochemistry and Biophysics

Year:

2002

Language:

english

File:

PDF, 132 KB

english, 2002

29

Tributyltin Causes Cytochrome c Release from Isolated Mitochondria by Two Discrete Mechanisms

Vladimir Gogvadze, Helene Stridh, Sten Orrenius, Ian Cotgreave

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 103 KB

english, 2002

30

The effect of butylated hydroxytoluene, an inhibitor of lipid peroxidation, on the calcium-induced uncoupling of rat liver mitochondria

Sergei A. Novgorodov, Vladimir G. Gogvadze, Boris I. Medvedev, Valeryi P. Zinchenko

Journal:

Year:

1989

Language:

english

File:

PDF, 262 KB

english, 1989

31

Cyclosporine A protects mitochondria in an in vitro model of hypoxia/reperfusion injury

Vladimir Gogvadze, Christoph Richter

Journal:

Year:

1993

Language:

english

File:

PDF, 607 KB

english, 1993

32

Oxidants in mitochondria: from physiology to diseases

Christoph Richter, Vladimir Gogvadze, Renato Laffranchi, Ralph Schlapbach, Matthias Schweizer, Marianne Suter, Patrick Walter, Marcus Yaffee

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1995

Language:

english

File:

PDF, 648 KB

english, 1995

33

The Warburg effect and mitochondrial stability in cancer cells

Vladimir Gogvadze, Boris Zhivotovsky, Sten Orrenius

Journal:

Molecular Aspects of Medicine

Year:

2010

Language:

english

File:

PDF, 363 KB

english, 2010

34

Mitochondrial involvement in cell death

Sten Orrenius, Erik Norberg, Vladimir Gogvadze, Boris Zhivotovsky

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 42 KB

english, 2012

35

Fas-triggered phosphatidylserine exposure is modulated by intracellular ATP

Bettina Gleiss, Vladimir Gogvadze, Sten Orrenius, Bengt Fadeel

Journal:

Year:

2002

Language:

english

File:

PDF, 216 KB

english, 2002

36

Reactive oxygen species generated in different compartments induce cell death, survival, or senescence

Panieri, Emiliano, Gogvadze, Vladimir, Norberg, Erik, Venkatesh, Rithika, Orrenius, Sten, Zhivotovsky, Boris

Journal:

Free Radical Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 2.67 MB

english, 2013

37

Stimulation of plant growth by exposure to low level γ-radiation and magnetic field, and their possible mechanism of action

Aleksandr M. Kuzin, Maiya E. Vagabova, Mikhail M. Vilenchik, Vladimir G. Gogvadze

Journal:

Environmental and Experimental Botany

Year:

1986

Language:

english

File:

PDF, 289 KB

english, 1986

38

Peroxiredoxin V is essential for protection against apoptosis in human lung carcinoma cells

Andrey Kropotov, Vladimir Gogvadze, Oleg Shupliakov, Nikolay Tomilin, Vladimir B. Serikov, Nikolai V. Tomilin, Boris Zhivotovsky

Journal:

Experimental Cell Research

Year:

2006

Language:

english

File:

PDF, 507 KB

english, 2006

39

Citrate kills tumor cells through activation of apical caspases

Kruspig, BjÃ¶rn, Nilchian, Azadeh, Orrenius, Sten, Zhivotovsky, Boris, Gogvadze, Vladimir

Journal:

Cellular and Molecular Life Sciences

Year:

2012

Language:

english

File:

PDF, 511 KB

english, 2012

40

Multiple pathways of cytochrome c release from mitochondria in apoptosis

Gogvadze, Vladimir, Orrenius, Sten, Zhivotovsky, Boris

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2006

Language:

english

File:

PDF, 234 KB

english, 2006

41

Targeting mitochondria by α-tocopheryl succinate overcomes hypoxia-mediated tumor cell resistance to treatment

Kulikov, Andrey V., Vdovin, Alexander S., Zhivotovsky, Boris, Gogvadze, Vladimir

Journal:

Cellular and Molecular Life Sciences

Year:

2014

Language:

english

File:

PDF, 845 KB

english, 2014

42

Microsomal Glutathione Transferase 1 Protects Against Toxicity Induced by Silica Nanoparticles but Not by Zinc Oxide Nanoparticles

Shi, Jingwen, Karlsson, Hanna L., Johansson, Katarina, Gogvadze, Vladimir, Xiao, Lisong, Li, Jiangtian, Burks, Terrance, Garcia-Bennett, Alfonso, Uheida, Abdusalam, Muhammed, Mamoun, Mathur, Sanjay, M

Journal:

Year:

2012

Language:

english

File:

PDF, 1.81 MB

english, 2012

43

Mitochondria — a bullseye in cancer therapy

Gogvadze, Vladimir, Zhivotovsky, Boris

Journal:

Year:

2014

Language:

english

File:

PDF, 235 KB

english, 2014

44

Mitochondrial substrates in cancer: Drivers or passengers?

Kruspig, Björn, Zhivotovsky, Boris, Gogvadze, Vladimir

Journal:

Year:

2014

Language:

english

File:

PDF, 851 KB

english, 2014

45

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

Zhang, Xiaonan, Fryknäs, Mårten, Hernlund, Emma, Fayad, Walid, De Milito, Angelo, Olofsson, Maria Hägg, Gogvadze, Vladimir, Dang, Long, Påhlman, Sven, Schughart, Leoni A. Kunz, Rickardson, Linda, D′Ar

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 4.36 MB

english, 2014

46

Targeting Hepatoma Using Nitric Oxide Donor Strategies

González, Raúl, Ferrín, Gustavo, Aguilar-Melero, Patricia, Ranchal, Isidora, Linares, Clara I., Bello, Rosario I., De la Mata, Manuel, Gogvadze, Vladimir, Bárcena, José A., Álamo, José M., Orrenius, S

Journal:

Antioxidants & Redox Signaling

Year:

2013

Language:

english

File:

PDF, 991 KB

english, 2013

47

Mitochondrial cytochrome c release may occur by volume-dependent mechanisms not involving permeability transition

GOGVADZE, Vladimir, ROBERTSON, John D., ENOKSSON, Mari, ZHIVOTOVSKY, Boris, ORRENIUS, Sten

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 176 KB

english, 2004

48

Caspase-2 Permeabilizes the Outer Mitochondrial Membrane and Disrupts the Binding of Cytochrome c to Anionic Phospholipids

Enoksson, Mari, Robertson, John D., Gogvadze, Vladimir, Bu, Pengli, Kropotov, Andrey, Zhivotovsky, Boris, Orrenius, Sten

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 636 KB

english, 2004

49

Mitotic catastrophe and cancer drug resistance: A link that must to be broken

Denisenko, Tatiana V., Sorokina, Irina V., Gogvadze, Vladimir, Zhivotovsky, Boris

Journal:

Drug Resistance Updates

Year:

2016

Language:

english

File:

PDF, 1.48 MB

english, 2016

50

Contrasting effects of cardiac glycosides on cisplatinand etoposide-induced cell death

Kulikov, Andrey V., Slobodkina, Ekaterina A., Alekseev, Andrey V., Gogvadze, Vladimir, Zhivotovsky, Boris

Journal:

Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 553 KB

english, 2016

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